Estibox® Pro Numb Rx is a prescription-strength topical anesthetic cream containing Benzocaine 20%, Lidocaine 10%, and Tetracaine 10% in a 30 g tube.

Specially designed for aesthetic and dermatology practices, this triple-anesthetic cream provides fast, effective numbing relief to help clients remain comfortable during procedures such as:

• Microneedling

• Chemical peels

• Laser resurfacing

• Dermal fillers and injectables

• PMU (permanent makeup) and tattooing

• Other in-office esthetic treatments

• Benzocaine 20%: Quick onset for surface numbing.

• Lidocaine 10%: Reliable, localized anesthetic effect.

• Tetracaine 10%: Long-lasting comfort throughout procedures.

Important Safety Information

• Prescription-only, dispensed under physician direction for esthetic/clinical use.
• For external use only; avoid contact with eyes, mouth, and mucous membranes.
• Do not apply to broken skin unless directed by a physician.
• Possible side effects include redness, burning, or temporary irritation.
• Rare systemic effects may occur if over-applied; always use the minimum effective dose.
• Contraindicated in patients with known hypersensitivity to ester- or amide-type anesthetics.

Packaged in a 30 g tube, Estibox® Pro Numb Rx offers estheticians a professional-grade numbing solution to support client comfort before cosmetic procedures.

Frequently Asked Questions 

What is Estibox® Pro Numb Rx?
A prescription-strength triple-anesthetic cream with benzocaine 20%, lidocaine 10%, and tetracaine 10%, designed for professional use before esthetic and dermatologic procedures.

How is it applied?
Apply a thin, even layer to the treatment area 20–40 minutes before the procedure, then remove excess before beginning. Follow provider protocols.

How long does the numbing last?
Most patients experience numbness within minutes, lasting through standard cosmetic procedures.

Is it safe?
Yes, under professional supervision. Overuse or incorrect application may increase risk of irritation or systemic effects.

Can estheticians dispense this to clients?
No, Clients should schedule their pretreatment telehealth session and use it under physician guidance before procedures, as directed.

Who should not use this product?
Patients allergic to local anesthetics, or those with certain medical conditions (cardiac, respiratory) should avoid use without clearance from a physician.